beta Catenin anticorps

N° du produit ABIN4949463

Cet anticorps Souris Monoclonal détecte spécifiquement beta Catenin dans WB et IF. Il présente une réactivité envers Humain, Poulet, Boeuf (Vache) et Chien.

Aperçu rapide pour beta Catenin anticorps (ABIN4949463)

Antigène: beta Catenin (CATNB) (Catenin, beta (CATNB))

Reactivité: Humain, Poulet, Boeuf (Vache), Chien

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp beta Catenin est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Clone: 9F2

Détail du produit anti-beta Catenin anticorps

Purification: Protein G affinity chromatography

Immunogène: Chicken b-Catenin was used as the immunogen for the b-Catenin antibody.

Isotype: IgG1 kappa

Information d'application

Indications d'application: Titration of the b-Catenin antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Immunofluorescence: 1-2 μg/mL,WB: 1-2 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the b-Catenin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Détails sur beta Catenin

Antigène: beta Catenin (CATNB) (Catenin, beta (CATNB))

Autre désignation: Beta Catenin

Sujet: The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. [RefSeq]

Pathways: Peptide Hormone Metabolism